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MAOIs taken with pethidine have been associated with intense CNS excitation or depression (including hypertension or hypotension). Whilst this hasn't been documented with codeine, it can be done that an identical interaction could occur and therefore the usage of codeine really should be averted although the affected individual is using MAOIs and for 2 months following MAOI discontinuation.

3). All young children received doses of codeine that were in the right dose variety; nonetheless there was evidence that these youngsters ended up both ultra-quick or intensive metabolisers within their capacity to metabolise codeine to morphine.

Using narcotics for some time may cause serious constipation. To avoid this, your health practitioner could direct you to definitely acquire laxatives, drink lots of fluids, or improve the quantity of fiber in the food plan.

By selecting this button you are confirming that you'll be a affected individual who has long been prescribed a Teva drugs by a British isles Health care Qualified (or their caregiver).

Before starting therapy with opioids, a discussion should be held with people to put set up a strategy for ending remedy with codeine in order to minimise the chance of habit and drug withdrawal syndrome (see section 4.four).

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Domperidone and metoclopramide: codeine antagonises the impact of cisapride, metoclopramide and domperidone on gastrointestinal exercise.

If you have any Uncomfortable side effects, check with your doctor or pharmacist. This consists of any possible Uncomfortable side effects not shown With this leaflet. See portion 4.

Anaesthetics: concomitant administration of codeine and anaesthetics may possibly trigger elevated CNS melancholy and/or respiratory depression and/or hypotension.

- Gastro-intestinal click here surgery – use with caution right after current GI surgical procedure as opioids may perhaps change GI motility.

Administration to nursing Females just isn't recommended as codeine phosphate could possibly be secreted in breast milk and could lead to respiratory despair within the toddler.

Overuse or misuse may well cause overdose and/or Demise. It is important that clients only use medicines which might be prescribed for them within the dose they happen to be prescribed and do not give this drugs to more info any person else.

This drugs has been prescribed for adults for reduction of discomfort, reduction of coughing and symptomatic aid of prolonged free stools (diarrhoea) and for kids above twelve many years of age for that brief-expression relief of average suffering that isn't relieved by other painkillers for example paracetamol or ibuprofen by itself.

Codeine or other narcotics may obscure indications on which to evaluate the analysis or scientific course of people with acute abdominal conditions.

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